JCPP Editorial: Volume 57, Issue 06, June 2016

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Editorial: Maturing insights into the genetic architecture of neurodevelopmental disorders – from common and rare variant interplay to precision psychiatry

Klaus-Peter Lesch


The categorisation of neurodevelopmental and psychiatric disorders by clinical syndromes, rather than by aetiology, continues to obstruct progress in biomarker identification as well as innovative drug development and effective treatment in general. There is a decisive move to think of neurodevelopmental disorders as a spectrum rather than discrete categorical entities. We might call them neurodevelopmental spectrum disorders (NSDs) ranging from intellectual disability (ID) to autism (ASD), and attention-deficit/hyperactivity disorder (ADHD) (Kiser, Rivero, & Lesch, 2015).

We hope you enjoy the full editorial of this Issue, which is free on the Wiley Online Library.


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