Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry

Bringing you some selected Open Access journal papers from our portfolio; The Journal of Child Psychology and Psychiatry (JCPP), Child and Adolescent Mental Health journal (CAMH), and JCPP Advances.

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‘Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry’

Open Access paper from the JCPP

Depression and anxiety are the most common mental health problems in young people. Currently, clinicians are advised to wait before initiating treatment for young people with these disorders as many spontaneously remit. However, others develop recurrent disorder but this subgroup cannot be identified at the outset. We examined whether psychiatric polygenic scores (PGS) could help inform stratification efforts to predict those at higher risk of recurrence.

Authors: Charlotte A. Dennison, Joanna Martin, Amy Shakeshaft, Lucy Riglin, Frances Rice, Cathryn M. Lewis, Michael C. O’Donovan, Anita Thapar

First published: 19 July 2023

https://doi.org/10.1111/jcpp.13862

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