Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial

Bringing you some selected Open Access journal papers from our portfolio; The Journal of Child Psychology and Psychiatry (JCPP), Child and Adolescent Mental Health journal (CAMH), and JCPP Advances.

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‘Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial’

Paper from the JCPP

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and interaction. Crucial for efficient social interaction is the ability to quickly and accurately extract information from a person’s face. Frequency-tagging electroencephalography (EEG) is a novel tool to quantify face-processing sensitivity in a robust and implicit manner. In terms of intervention approaches, intranasal administration of oxytocin (OT) is increasingly considered as a potential pharmacological approach for improving socio-communicative difficulties in ASD, through enhancing social salience and/or reducing (social) stress and anxiety.

Authors: Matthijs Moerkerke, Nicky Daniels, Stephanie Van der Donck, Laura Tibermont, Tiffany Tang, Edward Debbaut, Annelies Bamps, Jellina Prinsen, Jean Steyaert, Kaat Alaerts, Bart Boets

First published: 06 June 2023

https://doi.org/10.1111/jcpp.13850

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